Copper is a required cofactor for lysyl oxidase (connective-tissue crosslinking), for superoxide dismutase (antioxidant defense), and for enzymes that support angiogenesis, so a molecule that delivers copper in a controlled, cell-usable form has a coherent reason to influence tissue remodeling and vascular biology
doi: 10.1016/j.scib.2023.06.003 8 RahmaniAToloueitabarYMohsenzadehYHemmatiRSayehmiriKAsadollahiK
The study reveals that this regulator ensures proteins are folded correctly, a process that, when broken, leads to the toxic clogs found in neurodegenerative diseases and cancer
J Nutr 132:283288 Jacques PF, Bostom AG, Selhub J, Rich S, Ellison RC, Eckfeldt JH et al (2003) Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study