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Johnston, G

Antitumor effect of organometallic half-sandwich Ru(II)-Arene complexes bearing a glutathione S-Transferase inhibitor

The impact of GPE on cell proliferation, migration, and survival was examined under basal conditions and in response to a wound-healing assay, relative to two other treatment groups: growth hormone (GH) and GPE + GH groups

Current theories concerning disease pathogenesis include an imbalance between protease and anti-protease activity, induced apoptosis of alveolar cells through deregulation of pathways involved in oxidative stress, chronic inflammation, and aberrant tissue remodeling that lead to the destruction of the extracellular matrix (ECM) in the lung [3, 4]