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This idea comes from a smaller study published in The Journal of Clinical and Aesthetic Dermatology

Furthermore, studies using DSSinduced colitis models demonstrated significantly increased syn expression in the colon and notable syn deposits in the brain [132], supporting the hypothesis that the gastrointestinal tract serves as an initial site for syn pathology, which may then propagate to the CNS via the vagus nerve [23]

July 2016a

The FDA evaluation found insufficient evidence to establish effectiveness for the nominated use and highlighted gaps in physicochemical characterisation, immunogenicity and safety information