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It is derived fragment of human growth hormone (fragment 176-191) known mainly for its lipolytic qualities, which in research have been associated with the stimulation of body fat metabolism without the negative side effects mainly reported with common weight loss drugs

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Dysfunction of AMPK in nematodes can eliminate the longevity-prolonging function caused by metformin

Polydatin may act as a potent vascular endothelial protector in diabetes, and acetylcholine-induced vasodilation and endothelial disruption due to high glucose can be restored by polydatin in a dose-dependent manner [116]