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A 2015 meta-analysis of nine observational studies found a 2.5 times higher risk of thiamin deficiency in patients with heart failure compared to control subjects (78)

some felt that it was super hydrating but didn't do much in terms of wrinkle reduction

doi: 10.1111/jpi.12208 220 ShanJJinHXuY

This homeostatic behavior of Hcy is intriguing: It runs counter to the clinical observation that vitamin B 12 deficiency results in hyperhomocysteinemia