Furthermore, GSTs are additionally identified as regulators of cellular signaling pathways, thereby influencing cell proliferation or apoptosis ( in vitro with chemically reactive metabolites derived from several drugs displaying idiosyncratic toxicity, including troglitazone, acetaminophen, clozapine, and diclofenac (Vredenburg et al., 2014
Inside the liver, glutathione combines with toxins, heavy metals, and toxins, converting them into water-soluble compounds that are easily eliminated by the body
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[DOI] [PMC free article] [PubMed] [Google Scholar] 153.Gorlova OY et al
