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Amjad H, Carmichael D, Austin AM, Chang CH, Bynum JP

In a 36-week paired liver biopsy study (NCT02912260), markers of fibrosis were reduced significantly by Resmetirom treatment, including the reductions in LS ( p = 0.015) and the ratio of PRO-C3 (N-terminal type III collagen pro-peptide)/C3M (metalloproteinase-degraded collagen III) ( p = 0.0004), a proposed measure of net fibrosis formation, in adult patients with NASH

There is an emerging consensus that situations of acute or chronic imbalance between the antioxidative capacity of cells and tissues, and the production of pro oxidative species, is associated with the development of a number of human diseases

Leukemia 15 (10), 16331640