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A key experiment to differentiate these models involves using a pulse-chase to track the fate of newly synthesized GNPT in the absence of LYSET

Some patients may achieve sufficient lifestyle modifications and metabolic improvements to attempt medication discontinuation under medical supervision, while others may require indefinite therapy to maintain benefits

The results indicated that GSH levels in blood increased significantly after one, three, and six months compared to baseline in both the low-dose and high-dose GSH groups, while no such increase was observed in the placebo group